According to the Department of Psychiatry at the University of North Carolina, children with the mildest cases of autism after receiving ESDM therapy can become "indistinguishable" from children who are not on the spectrum as result of changes in their brain. Similarly, research published in the Journal of the American Academy of Child and Adolescent Psychiatry also found that the ESDM therapy can normalise brain functioning for children with mild autism symptoms.

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Following 5 years of randomised clinical trials for ESDM, the University of Washington found that children who received ESDM therapeutic intervention had on average an increase in IQ score of 17.6 points compared to 4 points for children attending other community-based therapy programs. The study also showed that children who have received 2 years of more of ESDM therapy for 20 hours per week had greater improvements in language and cognitive abilities and adaptive behaviour, and had fewer autism symptoms than the children who received other interventions.

ESDM is recognised, taught and studied at Australian universities which are leading in the field of diagnosis, therapy and treatment for autism.

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Publications can be found from links below.